UVRAG Rabbit Polyclonal Antibody (CAB8462)
- SKU:
- CAB8462
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | UVRAG Rabbit Polyclonal Antibody |
SKU: | CAB8462 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 501-699 of human UVRAG (NP_003360.2). |
Sequence: | KGHR KRAS SENE RLQY KTPP PSYN SALA QPVT TVPS MGET ERKI TSLS SSLD TSLD FSKE NKKK GEDL VGSL NGGH ANVH PSQE QGEA LSGH RATV NGTL LPSE QAGS ASVQ LPGE FHPV SEAE LCCT VEQA EEII GLEA TGFA SGDQ LEAF NCIP VDSA VAVE CDEQ VLGE FEEF SRRI YALN ENVS SFRR PRRS SDK |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | p63; DHTX; VPS38; UVRAG |
Positive Sample: | LO2,HeLa,Mouse liver,Rat liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Early endosome, Endoplasmic reticulum, Late endosome, Lysosome, Midbody, centromere. |
Calculated MW: | 78kDa |
Observed MW: | 100kDa |
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
Purification Method: | Affinity purification |
Gene ID: | 7405 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |