The UTP23 Polyclonal Antibody (PAC041234) is a vital tool for researchers studying UTP23, a protein involved in RNA processing and ribosome biogenesis. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the UTP23 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential tool for research in molecular biology and genetics.UTP23 is a key player in RNA metabolism, specifically in the maturation of ribosomal RNA and assembly of ribosomes. Dysregulation of UTP23 has been linked to various diseases, including cancer and genetic disorders affecting ribosome function.
By studying the function and regulation of UTP23, researchers can gain valuable insights into these disease processes and potentially identify new therapeutic targets for treatment.With its high specificity and sensitivity, the UTP23 Polyclonal Antibody is a valuable asset for scientists investigating the intricate mechanisms of RNA processing and ribosome biogenesis. By uncovering the roles of UTP23 in cellular processes, researchers can advance our understanding of gene expression and potentially develop novel strategies for combating disease.
Western blot. All lanes: UTP23 antibody at 7µg/ml + Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 29, 17 kDa. Observed band size: 29 kDa.
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO41234 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human liver cancer using PACO41234 at dilution of 1:100.
Background:
Involved in rRNA-processing and ribosome biogenesis.
Synonyms:
rRNA-processing protein UTP23 homolog, UTP23, C8orf53
UniProt Protein Function:
UTP23: Involved in rRNA-processing and ribosome biogenesis. Belongs to the UTP23/FCF1 family. UTP23 subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Nucleolus; RNA processingChromosomal Location of Human Ortholog: 8q24.11Cellular Component: small subunit processome; nucleolusBiological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
