The UTP18 Polyclonal Antibody (CAB15441) is a valuable tool for researchers studying UTP18, a protein involved in pre-ribosomal RNA processing and cell cycle regulation. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to UTP18, researchers can effectively detect and analyze the protein in a variety of cell types, making it an essential asset for studies in molecular biology and cancer research.
UTP18 is a crucial factor in ribosome biogenesis, playing a key role in the formation of ribosomal subunits essential for protein synthesis. Dysregulation of UTP18 has been linked to abnormal cell growth and proliferation, making it a potential target for cancer therapies. By investigating the function of UTP18, researchers can gain insights into the mechanisms underlying oncogenesis and potentially identify novel therapeutic strategies for treating cancer and other related diseases.
Product Name:
UTP18 Rabbit Polyclonal Antibody
SKU:
CAB15441
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 70-260 of human UTP18 (NP_057085.2).
Enables RNA binding activity. Predicted to be involved in rRNA processing. Located in nuclear membrane; nucleolus; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
51096
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using UTP18 Rabbit pAb (CAB15441) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.