The UTP14A Polyclonal Antibody (CAB5960) is specifically designed for research involving UTP14A, a protein involved in ribosomal RNA processing and ribosome biogenesis. This antibody is produced in rabbits and has high reactivity with human samples, making it ideal for use in Western blot applications. UTP14A is essential for the assembly and function of the small subunit of the ribosome, playing a critical role in protein synthesis. Research on UTP14A is crucial for understanding the mechanisms of ribosome biogenesis and its implications in diseases such as cancer, where dysregulation of protein synthesis can lead to uncontrolled cell growth.
By using the UTP14A Polyclonal Antibody, researchers can detect and analyze UTP14A expression in various cell types, providing valuable insights into its function in ribosome biogenesis and its potential as a therapeutic target in cancer research. This antibody is a powerful tool for studying the role of UTP14A in cellular processes and advancing our understanding of protein synthesis regulation.
Product Name:
UTP14A Rabbit Polyclonal Antibody
SKU:
CAB5960
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human UTP14A (NP_006640.2).
This gene encodes a member of the uridine triphosphate 14 family. As an essential component of a large ribonucleoprotein complex bound to the U3 small nucleolar RNA, the encoded protein is involved in ribosome biogenesis and 18S rRNA synthesis. An autosomal retrotransposed copy of this X-linked gene exists on chromosome 13. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10813
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using UTP14A Rabbit pAb (CAB5960) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
