USP8 Rabbit Polyclonal Antibody (CAB7031)
- SKU:
- CAB7031
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | USP8 Rabbit Polyclonal Antibody |
SKU: | CAB7031 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human USP8 (NP_005145.3). |
Sequence: | MPAV ASVP KELY LSSS LKDL NKKT EVKP EKIS TKSY VHSA LKIF KTAE ECRL DRDE ERAY VLYM KYVT VYNL IKKR PDFK QQQD YFHS ILGP GNIK KAVE EAER LSES LKLR YEEA EVRK KLEE KDRQ EEAQ RLQQ KRQE TGRE DGGT LAKG SLEN VLDS KDKT QKSN GEKN EKCE TKEK GAIT AKEL YTMM TDKN ISLI IMDA RRMQ DYQD SCIL HSLS VPEE AISP GVTA SWIE AHLP DDSK DTWK KRGN VEYV VLLD WFSS AKDL QI |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | UBPY; PITA4; SPG59; HumORF8; USP8 |
Positive Sample: | HeLa,MCF7,U-251MG,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Endosome membrane, Nucleus, Peripheral membrane protein. |
Calculated MW: | 128kDa |
Observed MW: | 140kDa |
This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 9101 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |