The USP7 Polyclonal Antibody (CAB13565) is a valuable tool for researchers studying USP7, a deubiquitinating enzyme with important roles in cellular processes such as DNA repair, cell cycle regulation, and immune response. This antibody, raised in rabbits, is highly specific to USP7 in human samples and is ideal for Western blot applications.USP7, also known as HAUSP, is known to regulate the stability and activity of various proteins involved in key cellular pathways, making it a potential target for therapeutic intervention in diseases such as cancer and neurodegenerative disorders.
By using the USP7 Polyclonal Antibody, researchers can accurately detect and quantify USP7 levels in different cell types, allowing for precise analysis and further understanding of its functions.With its high specificity and reliability, the USP7 Polyclonal Antibody is a valuable tool for researchers in the fields of molecular biology, oncology, and immunology who are interested in unraveling the complex roles of USP7 in health and disease.
Product Name:
USP7/HAUSP Rabbit Polyclonal Antibody
SKU:
CAB13565
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 206-1102 of human USP7/HAUSP (NP_003461.2).
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.
Purification Method:
Affinity purification
Gene ID:
7874
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using USP7/HAUSP Rabbit pAb (CAB13565) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
