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USP45 Antibody (PACO36722)

SKU:
PACO36722
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • USP45 Antibody PACO36722
  • USP45 Antibody PACO36722
€339
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Description

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USP45 Antibody (PACO36722)

The USP45 Polyclonal Antibody (PAC036722) is a vital tool for researchers studying USP45, a member of the ubiquitin-specific protease (USP) family involved in regulating protein degradation and cellular signaling pathways. This antibody, produced in rabbits, has high specificity and sensitivity for detecting USP45 in human samples, making it suitable for use in Western blot applications.USP45 is known to play a role in various cellular processes, including DNA repair, cell cycle progression, and immune response regulation.

Dysregulation of USP45 has been implicated in several diseases, such as cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions. This antibody allows for precise detection and analysis of USP45 levels in different cell types, providing valuable insights for research in cancer biology, neurobiology, and drug development efforts.

Antibody Name:USP45 Antibody (PACO36722)
Antibody SKU:PACO36722
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:Human
Immunogen:Recombinant Human Ubiquitin carboxyl-terminal hydrolase 45 protein (1-240AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageImmunohistochemistry of paraffin-embedded human testis tissue using PACO36722 at dilution of 1:100.
Product ImageImmunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO36722 at dilution of 1:100.
Background:Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal.
Synonyms:Ubiquitin carboxyl-terminal hydrolase 45 (EC 3.4.19.12) (Deubiquitinating enzyme 45) (Ubiquitin thioesterase 45) (Ubiquitin-specific-processing protease 45), USP45
UniProt Protein Function:USP45: Belongs to the peptidase C19 family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 3.4.19.12; Ubiquitin-specific protease; Protease; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 6q16.2

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function:ubiquitin-specific protease activity

Biological Process: DNA repair; protein deubiquitination

UniProt Code:Q70EL2
NCBI GenInfo Identifier:296453002
NCBI Gene ID:85015
NCBI Accession:Q70EL2.3
UniProt Secondary Accession:Q70EL2,Q5T062, Q86T44, Q86TC0, Q9BRU1, B2RXG0,
UniProt Related Accession:Q70EL2
Molecular Weight:55,812 Da
NCBI Full Name:Ubiquitin carboxyl-terminal hydrolase 45
NCBI Synonym Full Names:ubiquitin specific peptidase 45
NCBI Official Symbol:USP45  
NCBI Protein Information:ubiquitin carboxyl-terminal hydrolase 45
UniProt Protein Name:Ubiquitin carboxyl-terminal hydrolase 45
UniProt Synonym Protein Names:Deubiquitinating enzyme 45; Ubiquitin thioesterase 45; Ubiquitin-specific-processing protease 45
Protein Family:Ubiquitin carboxyl-terminal hydrolase
UniProt Gene Name:USP45  
UniProt Entry Name:UBP45_HUMAN
Antibodies
USP45 Antibody (PACO05556)
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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