The USP45 Polyclonal Antibody (PAC022673) is a valuable tool for researchers studying USP45, a deubiquitinating enzyme involved in regulating protein stability and function. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for Western blot analyses and other experimental techniques. By binding to the USP45 protein, this antibody enables researchers to investigate the role of USP45 in various cellular processes, particularly in the context of cancer and other diseases.USP45, also known as ubiquitin-specific protease 45, plays a critical role in maintaining protein homeostasis by removing ubiquitin molecules from target proteins.
Dysregulation of USP45 has been implicated in the pathogenesis of certain cancers and neurodegenerative disorders, making it a promising target for therapeutic intervention. By studying the function of USP45 using this polyclonal antibody, researchers can gain valuable insights into the mechanisms underlying disease progression and potentially identify new therapeutic strategies.
Antibody Name:
USP45 Antibody (PACO22673)
Antibody SKU:
PACO22673
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human USP45.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from A549 cells, using USP45 antibody.
Background:
Belongs to the peptidase C19 family. 3 isoforms of the human protein are produced by alternative splicing.
