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USP45 Antibody (PACO13137)

SKU:
PACO13137
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

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USP45 Antibody (PACO13137)

The USP45 Polyclonal Antibody (PAC013137) is a valuable tool for researchers studying USP45, a protein involved in cellular homeostasis and signaling pathways. This antibody, produced in rabbits, boasts high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the USP45 protein, this antibody allows for the detection and analysis of USP45 in a variety of cell types, making it ideal for studies in molecular biology and cell signaling research.USP45, a deubiquitinating enzyme, plays a crucial role in maintaining the balance of proteins in cells by regulating the ubiquitin-proteasome system.

Dysregulation of USP45 has been linked to various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions. Researchers investigating USP45 aim to further understand its function and potential as a therapeutic target for these diseases.By utilizing the USP45 Polyclonal Antibody, researchers can gain valuable insights into the role of USP45 in cellular processes and disease pathways, ultimately paving the way for potential advancements in the development of targeted therapies.

Antibody Name:USP45 Antibody (PACO13137)
Antibody SKU:PACO13137
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human USP45
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:ubiquitin specific peptidase 45;USP45;MGC14793 ;
UniProt Protein Function:USP45: Belongs to the peptidase C19 family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 3.4.19.12; Ubiquitin-specific protease; Protease; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 6q16.2

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function:ubiquitin-specific protease activity

Biological Process: DNA repair; protein deubiquitination

UniProt Code:Q70EL2
NCBI GenInfo Identifier:296453002
NCBI Gene ID:85015
NCBI Accession:Q70EL2.3
UniProt Secondary Accession:Q70EL2,Q5T062, Q86T44, Q86TC0, Q9BRU1, B2RXG0,
UniProt Related Accession:Q70EL2
Molecular Weight:55,812 Da
NCBI Full Name:Ubiquitin carboxyl-terminal hydrolase 45
NCBI Synonym Full Names:ubiquitin specific peptidase 45
NCBI Official Symbol:USP45  
NCBI Protein Information:ubiquitin carboxyl-terminal hydrolase 45
UniProt Protein Name:Ubiquitin carboxyl-terminal hydrolase 45
UniProt Synonym Protein Names:Deubiquitinating enzyme 45; Ubiquitin thioesterase 45; Ubiquitin-specific-processing protease 45
Protein Family:Ubiquitin carboxyl-terminal hydrolase
UniProt Gene Name:USP45  
UniProt Entry Name:UBP45_HUMAN

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