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USP45 Antibody (PACO05556)

SKU:
PACO05556
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
Frequently bought together:

Description

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USP45 Antibody (PACO05556)

The USP45 Polyclonal Antibody (PACO05556) is a valuable tool for researchers studying USP45, a protein involved in the regulation of cellular processes such as protein degradation and DNA repair. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, making it an ideal choice for applications such as Western blotting.USP45, a deubiquitinase enzyme, plays a critical role in maintaining protein quality control and stability by removing ubiquitin molecules from target proteins. Dysregulation of USP45 has been linked to various diseases including cancer, neurodegenerative disorders, and metabolic diseases.

By utilizing this antibody, researchers can gain insight into the function of USP45 and its potential implications in disease pathology.With its ability to specifically detect USP45 in various cell types, this antibody is a valuable asset for studies in molecular biology, cell signaling, and drug development. By understanding the role of USP45 in cellular processes, researchers can pave the way for the development of novel therapeutic strategies targeting USP45-related pathways.

Antibody Name:USP45 Antibody (PACO05556)
Antibody SKU:PACO05556
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:ELISA:1:10000, WB:1:500-1:2000
Species Reactivity:Human, Mouse, Rat
Immunogen:Synthesized peptide derived from the Internal region of human USP45.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:USP45; Ubiquitin carboxyl-terminal hydrolase 45; Deubiquitinating enzyme 45; Ubiquitin thioesterase 45; Ubiquitin-specific-processing protease 45
UniProt Protein Function:USP45: Belongs to the peptidase C19 family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 3.4.19.12; Ubiquitin-specific protease; Protease; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 6q16.2

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function:ubiquitin-specific protease activity

Biological Process: DNA repair; protein deubiquitination

UniProt Code:Q70EL2
NCBI GenInfo Identifier:296453002
NCBI Gene ID:85015
NCBI Accession:Q70EL2.3
UniProt Secondary Accession:Q70EL2,Q5T062, Q86T44, Q86TC0, Q9BRU1, B2RXG0,
UniProt Related Accession:Q70EL2
Molecular Weight:55,812 Da
NCBI Full Name:Ubiquitin carboxyl-terminal hydrolase 45
NCBI Synonym Full Names:ubiquitin specific peptidase 45
NCBI Official Symbol:USP45  
NCBI Protein Information:ubiquitin carboxyl-terminal hydrolase 45
UniProt Protein Name:Ubiquitin carboxyl-terminal hydrolase 45
UniProt Synonym Protein Names:Deubiquitinating enzyme 45; Ubiquitin thioesterase 45; Ubiquitin-specific-processing protease 45
Protein Family:Ubiquitin carboxyl-terminal hydrolase
UniProt Gene Name:USP45  
UniProt Entry Name:UBP45_HUMAN

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