The USP44 Polyclonal Antibody (CAB15528) is a valuable tool for researchers studying USP44, a deubiquitinating enzyme with important roles in regulating cell cycle progression and DNA damage response. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blotting applications.USP44 is known to play a crucial role in maintaining genome stability by controlling the levels of key regulatory proteins involved in cell division and DNA repair.
Dysregulation of USP44 has been implicated in various human diseases, including cancer, making it a potential target for therapeutic interventions.By using the USP44 Polyclonal Antibody, researchers can detect and quantify USP44 protein levels in different cell types and experimental conditions, allowing for a better understanding of its function and potential implications in disease states. This antibody is a valuable resource for studies in cancer biology, cell cycle regulation, and DNA repair mechanisms.
Product Name:
USP44 Rabbit Polyclonal Antibody
SKU:
CAB15528
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-270 of human USP44 (NP_115523.2).
The protein encoded by this gene is a protease that functions as a deubiquitinating enzyme. The encoded protein is thought to help regulate the spindle assembly checkpoint by preventing early anaphase onset. This protein specifically deubiquitinates CDC20, which stabilizes the anaphase promoting complex/cyclosome.
Purification Method:
Affinity purification
Gene ID:
84101
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using USP44 Rabbit pAb (CAB15528) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
