The USP43 Polyclonal Antibody (PACO02464) is a valuable tool for research involving USP43, a protein involved in cellular processes such as DNA repair, cell cycle regulation, and protein degradation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot and immunohistochemistry applications.USP43, a deubiquitinating enzyme, plays a key role in maintaining genomic stability and regulating the turnover of proteins involved in critical cellular functions.
Its dysregulation has been implicated in diseases such as cancer and neurodegenerative disorders, making it a promising target for therapeutic intervention. The USP43 Polyclonal Antibody allows for the detection and analysis of USP43 expression levels in different cell types and tissues, providing important insights for understanding its role in disease pathogenesis and identifying potential therapeutic strategies.
Antibody Name:
USP43 Antibody
Antibody SKU:
PACO02464
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the N-terminal region of human USP43.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
USP43: May recognize and hydrolyze the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly- ubiquitin precursors as well as that of ubiquitinated proteins. Belongs to the peptidase C19 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.4.19.12; Ubiquitin-specific protease; ProteaseChromosomal Location of Human Ortholog: 17p13.1Cellular Component: nucleoplasmMolecular Function: ISG15-specific protease activityBiological Process: bypass DNA synthesis
