The USP40 Polyclonal Antibody (CAB15856) is a vital tool for researchers studying USP40, a protein involved in the regulation of cellular processes. This antibody, produced in a rabbit host, exhibits high specificity and sensitivity towards USP40 in human samples, making it suitable for use in Western blot assays. By binding to the USP40 protein, this antibody allows for the visualization and quantification of USP40 expression in a variety of cell types, making it an ideal choice for investigations in cell biology and disease research.
USP40, a deubiquitinating enzyme, plays a crucial role in the maintenance of protein homeostasis by removing ubiquitin chains from target proteins. Dysregulation of USP40 has been implicated in various diseases, including cancer and neurodegenerative disorders, highlighting the importance of studying its functions. By elucidating the role of USP40 in cellular pathways, researchers can gain valuable insights into disease mechanisms and potentially identify novel therapeutic targets for intervention.
Product Name:
USP40 Rabbit Polyclonal Antibody
SKU:
CAB15856
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1173-1247 of human USP40 (NP_060688.1).
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).
Purification Method:
Affinity purification
Gene ID:
55230
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using USP40 Rabbit pAb (CAB15856) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
