The USP39 Antibody (PAC017394) is a highly specific and sensitive tool for researchers studying USP39, a key protein involved in RNA splicing and gene expression regulation. This polyclonal antibody, produced through immunization of rabbits, exhibits strong reactivity with USP39 in human samples and is ideal for Western blot applications.USP39, a spliceosome associated protein, plays a crucial role in the splicing of pre-mRNA and the maintenance of genomic stability. Dysregulation of USP39 has been linked to various diseases, including cancer and neurodegenerative disorders, making it an important target for therapeutic interventions. By using the USP39 Antibody, researchers can explore the function and regulation of USP39 in different cell types and gain insights into its implications in disease pathology.
The USP39 Antibody offers researchers a reliable tool for investigating the role of USP39 in cellular processes and disease mechanisms. Its high specificity and sensitivity make it a valuable asset for studies in molecular biology, cancer research, and drug development. By targeting USP39 with this antibody, researchers can deepen their understanding of RNA splicing and gene expression regulation, paving the way for new therapeutic approaches in a variety of pathological conditions.
Antibody Name:
USP39 Antibody (PACO17394)
Antibody SKU:
PACO17394
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:5000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human USP39
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Hepg2 cell, Primary antibody: PACO17394(USP39 Antibody) at dilution 1/400 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds.
Background:
USP39 (ubiquitin specific peptidase 39), also known as SAD1, CGI-21, HSPC332 or SNRNP65, is a 565 amino acid, nuclear protein belonging to the peptidase C19 family. Containing one UBP-type zinc finger, USP39 play a role in mRNA splicing and is part of a tri-snRNP complex. USP39 is thought to be required for the stabilization of the spindle checkpoint and may help support successful cytokinesis.
