The USP37 Polyclonal Antibody (CAB15593) is a valuable tool for researchers studying USP37, a deubiquitinating enzyme involved in various cellular processes, such as DNA repair, cell cycle regulation, and tumorigenesis. This antibody, raised in rabbits, exhibits high sensitivity and specificity for detecting USP37 in human samples, making it suitable for use in Western blot and immunohistochemistry applications.USP37, a member of the USP family of proteases, is known to deubiquitinate and stabilize target proteins, impacting cellular functions and signaling pathways. Dysregulation of USP37 has been linked to cancer development and progression, making it a potential therapeutic target in oncology research.
By studying the expression and activity of USP37, researchers can gain insights into its role in cancer biology and potentially identify new treatment strategies.Overall, the USP37 Polyclonal Antibody offers researchers a reliable tool for investigating the functions and implications of USP37 in cellular physiology and disease mechanisms. Its superior performance in detecting USP37 protein levels makes it an essential reagent for studies related to cancer biology, drug development, and molecular biology research.
Product Name:
USP37 Rabbit Polyclonal Antibody
SKU:
CAB15593
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human USP37 (NP_065986.2).
Enables cysteine-type endopeptidase activity; protein kinase binding activity; and thiol-dependent deubiquitinase. Involved in G1/S transition of mitotic cell cycle; protein deubiquitination; and regulation of DNA replication. Located in nucleus.
Purification Method:
Affinity purification
Gene ID:
57695
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using USP37 Rabbit pAb (CAB15593) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
