The USP33 Polyclonal Antibody (CAB16187) is a valuable tool for researchers studying USP33, a deubiquitinating enzyme involved in various cellular processes such as protein degradation, cell cycle regulation, and DNA repair. The antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in applications such as Western blotting.USP33 plays a crucial role in cellular signaling pathways, particularly those involved in cancer development, neurodegenerative diseases, and immune responses.
By targeting USP33, researchers can gain insights into the molecular mechanisms underlying these conditions and potentially identify new therapeutic targets.Furthermore, the USP33 Polyclonal Antibody (CAB16187) enables the detection and quantification of USP33 protein levels in different cell types, allowing for accurate and reliable analysis in immunology, oncology, and other research fields. Its versatility and reliability make it a valuable asset in the quest for understanding and combating various diseases at the molecular level.
Product Name:
USP33 Rabbit Polyclonal Antibody
SKU:
CAB16187
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 290-400 of human USP33 (NP_963920.1).
Cytoplasm, Golgi apparatus, centrosome, cytoskeleton, microtubule organizing center, perinuclear region
Calculated MW:
107kDa
Observed MW:
107kDa
This gene encodes a deubiquinating enzyme important in a variety of processes, including Slit-dependent cell migration and beta-2 adrenergic receptor signaling. The protein is negatively regulated through ubiquitination by von Hippel-Lindau tumor protein (VHL). Alternative splicing results in multiple transcript variants and protein isoforms.
Purification Method:
Affinity purification
Gene ID:
23032
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using USP33 Rabbit pAb (CAB16187) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1min.
