The USP30 Polyclonal Antibody (CAB12862) is a valuable tool for researchers studying the USP30 protein, a key regulator of mitochondrial quality control and dynamics. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards USP30 in human samples, making it ideal for use in Western blot applications.USP30 is a deubiquitinating enzyme located in the outer mitochondrial membrane, where it plays a crucial role in the maintenance of mitochondrial function and integrity. Dysregulation of USP30 has been implicated in various diseases, including neurodegenerative disorders and cancer, highlighting its importance as a therapeutic target.
By enabling the detection and analysis of USP30 in different cell types, the USP30 Polyclonal Antibody opens up opportunities for further research into the molecular mechanisms underlying mitochondrial quality control and its implications for human health. Its reliability and specificity make it an essential tool for investigators seeking to unravel the complex roles of USP30 in cellular homeostasis and disease pathogenesis.
Product Name:
USP30 Rabbit Polyclonal Antibody
SKU:
CAB12862
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 57-390 of human USP30 (NP_116052.2).
USP30, a member of the ubiquitin-specific protease family (see USP1, MIM 603478), is a novel mitochondrial deubiquitinating (DUB) enzyme (Nakamura and Hirose, 2008 [PubMed 18287522]).
Purification Method:
Affinity purification
Gene ID:
84749
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using USP30 Rabbit pAb (CAB12862) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
