The USP3 Polyclonal Antibody (CAB15769) is a valuable tool for researchers studying USP3, a deubiquitinating enzyme involved in the regulation of various cellular processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity in detecting USP3 protein in human samples, making it ideal for use in Western blot and immunohistochemistry applications.USP3 plays a crucial role in maintaining cellular homeostasis by controlling protein stability and turnover through the removal of ubiquitin chains. Dysregulation of USP3 activity has been implicated in the progression of various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions.
By studying the expression and function of USP3, researchers can gain insights into the mechanisms underlying these diseases and potentially identify novel therapeutic targets.The USP3 Polyclonal Antibody (CAB15769) provides researchers with a reliable tool to investigate the role of USP3 in cellular processes and disease pathogenesis. Its high specificity and sensitivity make it a valuable resource for studies aimed at understanding the molecular mechanisms controlled by USP3 and its potential implications for therapeutic interventions.
Product Name:
USP3 Rabbit Polyclonal Antibody
SKU:
CAB15769
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 321-520 of human USP3 (NP_006528.2).
Enables histone binding activity and thiol-dependent deubiquitinase. Involved in several processes, including DNA repair; histone deubiquitination; and regulation of protein stability. Located in several cellular components, including Flemming body; cytoplasmic ribonucleoprotein granule; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
9960
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from K-562 cells, using USP3 Rabbit pAb (CAB15769) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
