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USP28 Antibody (PACO13127)

SKU:
PACO13127
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
$551
Frequently bought together:

Description

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USP28 Antibody (PACO13127)

The USP28 Polyclonal Antibody (PACO13127) is a valuable tool for researchers studying the USP28 protein, which plays a crucial role in cellular processes such as DNA repair and cell cycle regulation. This antibody, produced in rabbits, shows high specificity and sensitivity for detecting USP28 in human samples, making it suitable for use in Western blot applications.USP28 is a deubiquitinating enzyme that is involved in controlling the stability and activity of various proteins within the cell. Dysregulation of USP28 has been linked to the development of cancer and other diseases, making it a promising target for therapeutic interventions.

By using the USP28 Polyclonal Antibody, researchers can investigate the expression and function of USP28 in different cell types, furthering our understanding of its role in disease pathology.Overall, the USP28 Polyclonal Antibody is a versatile tool for researchers interested in studying the molecular mechanisms underlying cellular processes and disease development. Its high reactivity and specificity make it a valuable resource for those working in the fields of molecular biology, cancer research, and drug discovery.

Antibody Name:USP28 Antibody (PACO13127)
Antibody SKU:PACO13127
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human USP28
Form:Liquid
Storage Buffer:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:ubiquitin specific peptidase 28;USP28;KIAA1515 ;
UniProt Protein Function:USP28: a peptidase of the C19 family. USP28 and FBXW7 regulate Myc protein stability in response to DNA damage. Two isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 3.4.19.12; Protease; Ubiquitin-specific protease

Chromosomal Location of Human Ortholog: 11q23.2

Cellular Component: nuclear body; nucleoplasm; protein complex

Molecular Function:protein binding; ubiquitin-specific protease activity

Biological Process: cell proliferation; DNA damage checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; protein deubiquitination; Ras protein signal transduction; regulation of protein stability; response to DNA damage stimulus; response to ionizing radiation

NCBI Summary:The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. [provided by RefSeq, Oct 2016]
UniProt Code:Q96RU2
NCBI GenInfo Identifier:20140700
NCBI Gene ID:57646
NCBI Accession:Q96RU2.1
UniProt Secondary Accession:Q96RU2,Q6NZX9, Q9P213, B0YJC0, B0YJC1,
UniProt Related Accession:Q96RU2
Molecular Weight:122kDa
NCBI Full Name:Ubiquitin carboxyl-terminal hydrolase 28
NCBI Synonym Full Names:ubiquitin specific peptidase 28
NCBI Official Symbol:USP28  
NCBI Protein Information:ubiquitin carboxyl-terminal hydrolase 28
UniProt Protein Name:Ubiquitin carboxyl-terminal hydrolase 28
UniProt Synonym Protein Names:Deubiquitinating enzyme 28; Ubiquitin thioesterase 28; Ubiquitin-specific-processing protease 28
Protein Family:Ubiquitin carboxyl-terminal hydrolase
UniProt Gene Name:USP28  

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