The USP25 Polyclonal Antibody (CAB12588) is a valuable tool for researchers studying the USP25 protein, a deubiquitinating enzyme that plays a crucial role in regulating protein stability and cellular processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the USP25 protein, this antibody allows for the detection and analysis of USP25 expression in a variety of cell types, making it ideal for studies in molecular biology and cell signaling pathways.USP25 is known for its involvement in diverse cellular functions, such as DNA repair, cell cycle regulation, and protein turnover.
Dysregulation of USP25 has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic diseases. Research on USP25 is crucial for understanding its role in these conditions and developing targeted therapies for addressing related pathologies.Overall, the USP25 Polyclonal Antibody is a valuable tool for researchers investigating the biological functions and therapeutic implications of the USP25 protein, offering insights into its role in disease progression and potential avenues for intervention.
Product Name:
USP25 Rabbit Polyclonal Antibody
SKU:
CAB12588
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human USP25 (NP_037528.3).
Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 [PubMed 10644437]).
Purification Method:
Affinity purification
Gene ID:
29761
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using USP25 antibody (CAB12588) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
