The USP24 Polyclonal Antibody (CABXXXXX) is a valuable tool for researchers studying USP24, a key enzyme involved in protein degradation and turnover. This antibody, produced in rabbits, has high specificity and sensitivity for detecting USP24 in human samples, making it ideal for Western blot applications. By targeting USP24, this antibody allows for the examination of protein turnover dynamics and the regulation of cellular processes.USP24, a member of the deubiquitinating enzyme family, plays a crucial role in maintaining protein homeostasis by removing ubiquitin groups from target proteins.
Dysregulation of USP24 activity has been implicated in various diseases, including cancer, neurodegenerative disorders, and immune-related conditions. As such, understanding the function of USP24 is essential for developing targeted therapies and interventions aimed at modulating protein degradation pathways.Overall, the USP24 Polyclonal Antibody offers researchers a valuable tool for investigating the role of USP24 in health and disease, opening up new possibilities for advancing our understanding of cellular processes and developing novel treatment strategies.
Product Name:
USP24 Polyclonal Antibody
SKU:
CAB21416
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2431-2620 of human USP24 (NP_056121.2).
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).
Purification Method:
Affinity purification
Gene ID:
23358
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using USP24 Rabbit pAb (CAB21416) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
