The USP22 Polyclonal Antibody (CAB17663) is a valuable tool for researchers studying USP22, a key player in regulating gene expression and cell proliferation. This antibody, produced in rabbits, specifically targets USP22 in human samples and is validated for use in Western blot applications. By binding to USP22, researchers can accurately detect and analyze the protein in various cell types, making it ideal for studies in cancer biology and epigenetics.USP22, a member of the deubiquitinating enzyme family, is involved in multiple cellular processes, including DNA damage repair, cell cycle progression, and transcriptional control.
Dysregulation of USP22 has been implicated in various cancers, highlighting its potential as a therapeutic target for anti-cancer drug development. Understanding the role of USP22 in cellular pathways is essential for unraveling its impact on disease progression and identifying new treatment strategies.
Product Name:
USP22 Rabbit Polyclonal Antibody
SKU:
CAB17663
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human USP22 (NP_056091.1).
Enables enzyme binding activity; nuclear receptor coactivator activity; and thiol-dependent deubiquitinase. Contributes to H4 histone acetyltransferase activity. Involved in positive regulation of mitotic cell cycle; positive regulation of transcription, DNA-templated; and protein modification by small protein conjugation or removal. Part of SAGA complex.
Purification Method:
Affinity purification
Gene ID:
23326
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using USP22 Rabbit pAb (CAB17663) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5min.
