The USP16 Polyclonal Antibody (CAB5861) is a valuable tool for researchers studying USP16, a key regulator of gene expression and cell growth. This antibody is produced in rabbits and has high reactivity specifically with human samples, making it ideal for Western blot applications. By targeting the USP16 protein, this antibody allows for precise detection and analysis in various cell types, facilitating research in areas such as cell biology, cancer biology, and drug development.USP16, also known as ubiquitin-specific protease 16, plays a crucial role in controlling the stability and function of various proteins involved in cell proliferation, differentiation, and DNA repair.
Dysregulation of USP16 has been implicated in cancer development and progression, making it a promising target for therapeutic interventions. By studying the function and regulation of USP16, researchers can gain insights into the molecular mechanisms underlying cancer and identify potential strategies for targeted therapy.
Product Name:
USP16 Rabbit Polyclonal Antibody
SKU:
CAB5861
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat,Monkey
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human USP16 (NP_001001992.1).
This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
10600
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using USP16 antibody (CAB5861) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
