The USP13 Polyclonal Antibody (CAB10264) is a valuable tool for researchers studying USP13, a cellular protein with key roles in regulating protein degradation and cell signaling pathways. This antibody, produced in rabbits, has a high affinity for USP13 in human samples and is validated for use in Western blot analyses. By binding specifically to the USP13 protein, this antibody enables researchers to detect and study USP13 in different cell types, making it an essential component for studies in cell biology and molecular biology.USP13, a deubiquitinating enzyme, is involved in various cellular processes such as DNA repair, cell cycle regulation, and protein stability.
Its dysregulation has been linked to diseases like cancer, neurodegenerative disorders, and inflammatory conditions. The USP13 Polyclonal Antibody provides a means to investigate the functions and mechanisms of USP13, shedding light on its potential as a therapeutic target for treating these diseases. Understanding the role of USP13 is critical for developing targeted therapies that can modulate cellular processes and improve patient outcomes.
Product Name:
USP13 Rabbit Polyclonal Antibody
SKU:
CAB10264
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 90-200 of human USP13 (NP_003931.2).
Enables several functions, including BAT3 complex binding activity; chaperone binding activity; and cysteine-type peptidase activity. Involved in several processes, including maintenance of unfolded protein involved in ERAD pathway; regulation of cellular catabolic process; and regulation of transcription, DNA-templated. Acts upstream of or within protein deubiquitination and protein stabilization. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nucleus.
Purification Method:
Affinity purification
Gene ID:
8975
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using USP13 antibody (CAB10264) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
