The USP10 Rabbit Monoclonal Antibody (CAB4454) is a valuable tool for researchers studying USP10, a protein involved in the regulation of cellular processes such as DNA repair and apoptosis. This antibody, derived from rabbits, demonstrates high specificity and sensitivity for detecting USP10 in human samples, making it ideal for Western blot applications.USP10, a deubiquitinating enzyme, plays a crucial role in maintaining cellular homeostasis by controlling the stability of various proteins involved in cell signaling pathways. Dysregulation of USP10 has been linked to tumorigenesis, neurodegenerative diseases, and immune disorders, highlighting its potential as a therapeutic target.
By using the USP10 Rabbit Monoclonal Antibody, researchers can further investigate the functions of USP10 in different cell types and disease models, providing valuable insights into its involvement in various physiological and pathological processes. This antibody serves as a valuable tool for studies in cancer biology, neuroscience, and immunology, offering new opportunities for drug discovery and therapeutic development.
Product Name:
USP10 Rabbit Monoclonal Antibody
SKU:
CAB4454
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human USP10 (Q14694).
Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9100
Clone Number:
ARC1015
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using USP10 Rabbit mAb (CAB4454) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.