The USP10 Polyclonal Antibody (CAB7505) is specifically designed for research involving USP10, a deubiquitinating enzyme that plays a critical role in various cellular processes. This antibody, generated in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the USP10 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal tool for immunology and cancer research studies.USP10 is known for its involvement in regulating the stability and activity of numerous proteins through the removal of ubiquitin molecules.
This enzymatic function has implications in various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions. Understanding the role of USP10 in these pathologies is essential for developing targeted therapies that can modulate protein stability and cellular function. By utilizing the USP10 Polyclonal Antibody (CAB7505), researchers can gain valuable insights into the mechanisms underlying these diseases and potentially uncover new therapeutic strategies for improving patient outcomes.
Product Name:
USP10 Rabbit Polyclonal Antibody
SKU:
CAB7505
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 499-798 of human USP10 (NP_005144.2).
Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9100
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using USP10 antibody (CAB7505) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
