USH1C Rabbit Polyclonal Antibody (CAB12556)
- SKU:
- CAB12556
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | USH1C Rabbit Polyclonal Antibody |
SKU: | CAB12556 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 264-533 of human USH1C (NP_001284693.1). |
Sequence: | VDFS NLDH KEGR ELFM TDRE RLAE ARQR ELQR QELL MQKR LAME SNKI LQEQ QEME RQRR KEIA QKAA EENE RYRK EMEQ IVEE EEKF KKQW EEDW GSKE QLLL PKTI TAEV HPVP LRKP KYDQ GVEP ELEP ADDL DGGT EEQG EQDF RKYE EGFD PYSM FTPE QIMG KDVR LLRI KKEG SLDL ALEG GVDS PIGK VVVS AVYE RGAA ERHG GIVK GDEI MAIN GKIV TDYT LAEA EAAL QKAW NQGG DWID LVVA VCPP KEYD DELT FF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PDZ73; AIE-75; DFNB18; PDZ-45; PDZ-73; PDZD7C; DFNB18A; NY-CO-37; NY-CO-38; ush1cpst; PDZ-73/NY-CO-38; USH1C |
Positive Sample: | 293T,HeLa,Mouse kidney,Mouse small intestine,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, cytoskeleton, cytosol. |
Calculated MW: | 62kDa |
Observed MW: | 62kDa |
This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10083 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |