USB1 Rabbit Polyclonal Antibody (CAB13229)
- SKU:
- CAB13229
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | USB1 Rabbit Polyclonal Antibody |
SKU: | CAB13229 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human USB1 (NP_078874.2). |
Sequence: | MSAA PLVG YSSS GSED ESED GMRT RPGD GSHR RGQS PLPR QRFP VPDS VLNM FPGT EEGP EDDS TKHG GRVR TFPH ERGN WATH VYVP YEAK EEFL DLLD VLLP HAQT YVPR LVRM KVFH LSLS QSVV LRHH WILP FVQA LKAR MTSF HRFF FTAN QVKI YTNQ EKTR TFIG LEVT SGHA QFLD LVSE VDRV MEEF NLTT FYQD PSFH LSLA WCVG DARL QLEG QCLQ ELQA IVDG FEDA EVLL RVHT EQVR CKSG NKFF SMPL K |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PN; Mpn1; HVSL1; hMpn1; hUsb1; C16orf57; USB1 |
Positive Sample: | 293T,A-431,HeLa,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 30kDa |
Observed MW: | 35kDa |
This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method: | Affinity purification |
Gene ID: | 79650 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |