The Uroplakin 3A Polyclonal Antibody (CAB10034) is a vital tool for researchers studying uroplakin 3A, a protein involved in the structure and function of the urinary bladder epithelium. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting uroplakin 3A in human samples, making it suitable for Western blot applications.Uroplakin 3A is a key component of urothelial cells, playing a crucial role in maintaining the integrity and barrier function of the bladder epithelium. Dysregulation of uroplakin 3A expression has been implicated in various bladder disorders and diseases, making it a target of interest in urological research.
By utilizing the Uroplakin 3A Polyclonal Antibody, researchers can accurately detect and analyze uroplakin 3A levels in different cell types and tissues, advancing our understanding of bladder physiology and pathology. This antibody is a valuable tool for investigations into bladder cancer, urinary tract infections, and other urological conditions where uroplakin 3A expression is altered.
Product Name:
UPK3A Rabbit Polyclonal Antibody
SKU:
CAB10034
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-207 of human UPK3A (NP_008884.1).
Endoplasmic reticulum membrane, Single-pass type I membrane protein.
Calculated MW:
31kDa
Observed MW:
30kDa
This gene encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Mutations in this gene may be associated with renal adysplasia. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
7380
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using UPK3A antibody (CAB10034) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
