The Urocortin-2 Polyclonal Antibody (CAB6485) is a powerful tool for researchers studying the protein Urocortin-2, a member of the corticotropin releasing factor (CRF) family involved in stress response and cardiovascular regulation. This antibody, produced in rabbits, specifically binds to Urocortin-2 in human samples and is validated for use in Western blotting applications.Urocortin-2 is known for its role in modulating cardiovascular function, energy metabolism, and stress response, making it a key target for research in cardiology, endocrinology, and neuroscience. By using this antibody, researchers can accurately detect and analyze the expression of Urocortin-2 in various cell types, shedding light on its physiological functions and potential therapeutic applications.
With its high reactivity and specificity, the Urocortin-2 Polyclonal Antibody is a valuable tool for advancing our understanding of Urocortin-2 biology and its implications in various diseases and physiological processes. Its use in research may lead to the development of novel treatments and interventions for conditions related to stress, cardiovascular dysfunction, and metabolic disorders.
Product Name:
UCN2 Rabbit Polyclonal Antibody
SKU:
CAB6485
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-112 of human UCN2 (NP_149976.1).
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.
Purification Method:
Affinity purification
Gene ID:
90226
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of rat skin, using UCN2 antibody (CAB6485) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
