The UQCRQ Polyclonal Antibody (CAB9872) is a valuable tool for researchers studying UQCRQ, a critical component of the mitochondrial respiratory chain complex III. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the UQCRQ protein, this antibody facilitates the detection and analysis of UQCRQ in various cell types, making it an essential tool for studies in bioenergetics, mitochondrial function, and diseases related to mitochondrial dysfunction.UQCRQ, also known as ubiquinol-cytochrome c reductase complex III subunit VII, is essential for the electron transport chain, playing a key role in ATP production and cellular respiration.
Dysregulation of UQCRQ has been linked to various diseases, including mitochondrial disorders, neurodegenerative diseases, and cancer. Research into the function and regulation of UQCRQ is critical for understanding the mechanisms underlying these conditions and developing potential therapeutic strategies targeting mitochondrial dysfunction. The UQCRQ Polyclonal Antibody (CAB9872) provides researchers with a reliable tool for investigating the role of UQCRQ in health and disease.
Product Name:
UQCRQ Rabbit Polyclonal Antibody
SKU:
CAB9872
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-82 of human UQCRQ (NP_055217.2).
This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain.
Purification Method:
Affinity purification
Gene ID:
27089
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using UQCRQ Rabbit pAb (CAB9872) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
