The UQCRFS1 Polyclonal Antibody (CAB14069) is a valuable tool for researchers studying the UQCRFS1 gene, which encodes a protein involved in mitochondrial respiratory chain complex III. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the UQCRFS1 protein, this antibody allows for the detection and analysis of this crucial component of the respiratory chain in various cell types.The UQCRFS1 gene plays a vital role in the electron transport chain, where it helps generate ATP, the cell's main source of energy.
Research into the function and regulation of UQCRFS1 is essential for understanding mitochondrial function and its implications for various diseases, including metabolic disorders, neurodegenerative diseases, and cancer. This antibody provides researchers with a reliable tool for investigating the role of UQCRFS1 in cellular metabolism and energy production, paving the way for new insights and potential therapeutic strategies.
Product Name:
UQCRFS1 Rabbit Polyclonal Antibody
SKU:
CAB14069
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 79-274 of human UQCRFS1 (NP_005994.2).
Predicted to enable oxidoreductase activity. Involved in mitochondrial respiratory chain complex III assembly and respiratory electron transport chain. Located in mitochondrion. Part of mitochondrial respiratory chain complex III and mitochondrial respiratory chain complex IV. Implicated in mitochondrial complex III deficiency.
Purification Method:
Affinity purification
Gene ID:
7386
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using UQCRFS1 antibody (CAB14069) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
