The UQCRC2 Rabbit Monoclonal Antibody (CAB4366) is a valuable tool for researchers studying the protein UQCRC2, which plays a crucial role in the electron transport chain in mitochondria. This antibody is produced using rabbit monoclonal technology, resulting in high specificity and sensitivity for detecting UQCRC2 in human samples. Validated for use in a variety of applications, including Western blot and immunohistochemistry, this antibody binds specifically to UQCRC2, allowing for precise detection and analysis in different cell types and tissues. Its reliability and consistency make it an ideal choice for studies in mitochondrial function, bioenergetics, and oxidative phosphorylation.
UQCRC2 is an essential component of complex III in the electron transport chain, responsible for transferring electrons and generating ATP in mitochondria. Dysregulation of UQCRC2 has been implicated in various diseases, including mitochondrial disorders, neurodegenerative diseases, and cancer. By studying UQCRC2 using this antibody, researchers can gain insights into mitochondrial dysfunction and its role in disease pathogenesis, paving the way for the development of novel therapeutic strategies targeting mitochondrial bioenergetics.
Product Name:
UQCRC2 Rabbit Monoclonal Antibody
SKU:
CAB4366
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human UQCRC2 (P22695).
The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5.
Purification Method:
Affinity purification
Gene ID:
7385
Clone Number:
ARC0982
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using UQCRC2 Rabbit mAb (CAB4366) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
