The UQCRC2 Polyclonal Antibody (CAB4181) is a valuable tool for researchers studying the UQCRC2 protein, a subunit of the mitochondrial respiratory chain complex III. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the UQCRC2 protein, this antibody enables accurate detection and analysis in various cell types, making it well-suited for research in biochemistry and mitochondrial biology.UQCRC2 plays a critical role in electron transfer and ATP production within the mitochondria, making it essential for cellular energy metabolism.
Dysregulation of UQCRC2 has been implicated in various metabolic disorders, making it a promising target for studying mitochondrial dysfunction and related diseases. By understanding the function of UQCRC2, researchers can gain insights into mechanisms underlying conditions such as metabolic syndromes, neurodegenerative diseases, and cancer, potentially leading to the development of targeted therapies.
Product Name:
UQCRC2 Rabbit Polyclonal Antibody
SKU:
CAB4181
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 224-453 of human UQCRC2 (NP_003357.2).
The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5.
Purification Method:
Affinity purification
Gene ID:
7385
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using UQCRC2 Rabbit pAb (CAB4181) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
