The UQCRC1 Polyclonal Antibody (CAB3339) is a valuable tool for researchers studying UQCRC1, a subunit of the mitochondrial cytochrome b-c1 complex involved in oxidative phosphorylation. This antibody, raised in rabbits, exhibits high reactivity with human samples and is ideal for use in Western blot applications. By binding to the UQCRC1 protein, this antibody enables researchers to detect and analyze UQCRC1 expression in various cell types, making it useful for investigations in the fields of bioenergetics, mitochondrial function, and diseases related to mitochondrial dysfunction.UQCRC1 is a crucial component of the electron transport chain, playing a vital role in generating ATP, the energy currency of the cell.
Dysregulation of UQCRC1 has been implicated in various diseases, including mitochondrial disorders, neurodegenerative diseases, and cancer. Understanding the function and regulation of UQCRC1 is essential for unraveling the molecular mechanisms underlying these conditions and identifying potential therapeutic targets. The UQCRC1 Polyclonal Antibody (CAB3339) provides researchers with a reliable tool to further explore the role of UQCRC1 in health and disease.
Product Name:
UQCRC1 Rabbit Polyclonal Antibody
SKU:
CAB3339
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 156-480 of human UQCRC1 (NP_003356.2).
Enables ubiquitin protein ligase binding activity. Predicted to be involved in oxidative phosphorylation. Predicted to act upstream of or within mitochondrial electron transport, ubiquinol to cytochrome c. Located in mitochondrion. Implicated in Alzheimer's disease. Biomarker of Alzheimer's disease.
Purification Method:
Affinity purification
Gene ID:
7384
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using UQCRC1 Rabbit pAb (CAB3339) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
