The UQCR11 Polyclonal Antibody (PAC031752) is a valuable tool for researchers studying the UQCR11 protein, a key component of the mitochondrial respiratory chain. This antibody, raised in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot and immunohistochemistry applications.UQCR11 is essential for the function of the respiratory chain, playing a crucial role in ATP production and cellular energy metabolism. Dysregulation of UQCR11 has been implicated in various diseases, including mitochondrial disorders and cancer.
By targeting the UQCR11 protein, researchers can gain insights into mitochondrial function and its role in disease pathology.This antibody provides researchers with a reliable tool for studying UQCR11 expression and localization in cells and tissues. Its specificity and sensitivity make it an ideal choice for investigations into mitochondrial function, bioenergetics, and disease mechanisms. Unlock the potential of your research with the UQCR11 Polyclonal Antibody from AssayGenie.
Antibody Name:
UQCR11 Antibody (PACO31752)
Antibody SKU:
PACO31752
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Cytochrome b-c1 complex subunit 10 protein (1-56AA)
Immunofluorescent analysis of Hela cells using PACO31752 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may be closely linked to the iron-sulfur protein in the complex and function as an iron-sulfur protein binding factor.
Synonyms:
Cytochrome b-c1 complex subunit 10 (Complex III subunit 10) (Complex III subunit XI) (Ubiquinol-cytochrome c reductase complex 6.4 kDa protein), UQCR11, UQCR
UniProt Protein Function:
UQCR: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. Belongs to the UQCR11/QCR10 family.Protein type: Mitochondrial; Energy Metabolism - oxidative phosphorylation; Oxidoreductase; Membrane protein, integral; EC 1.10.2.2Chromosomal Location of Human Ortholog: 19p13.3Cellular Component: mitochondrial inner membrane; integral to membraneMolecular Function: electron carrier activity; ubiquinol-cytochrome-c reductase activityBiological Process: cellular metabolic process; generation of precursor metabolites and energy
UniProt Protein Details:
NCBI Summary:
This gene encodes the smallest known component of the ubiquinol-cytochrome c reductase complex, which forms part of the mitochondrial respiratory chain. The encoded protein may function as a binding factor for the iron-sulfur protein in this complex. [provided by RefSeq, Oct 2009]
