The UQCR11 Polyclonal Antibody (PAC013100) is a valuable tool for researchers studying the UQCR11 protein, a key component of the mitochondrial respiratory chain complex III. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot assays. By specifically binding to UQCR11, this antibody allows for accurate detection and analysis of the protein in various cell types, making it an ideal choice for studies in mitochondrial biology and related fields.UQCR11 is essential for electron transport and ATP production in mitochondria, making it a crucial player in cellular energy metabolism. Dysregulation of UQCR11 has been linked to various mitochondrial disorders and metabolic diseases, highlighting its importance in maintaining proper mitochondrial function.
Research on UQCR11 is crucial for understanding the underlying mechanisms of these conditions and developing potential therapeutic interventions targeted at mitochondrial dysfunction.Overall, the UQCR11 Polyclonal Antibody (PAC013100) offers a reliable tool for investigating the role of UQCR11 in mitochondrial function and its implications for human health. Researchers in the field of biochemistry, cell biology, and mitochondrial genetics will find this antibody invaluable for their studies.
ubiquinol-cytochrome c reductase, 6.4kDa subunit;UQCR;0710008D09Rik;QCR10 ;
UniProt Protein Function:
UQCR: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. Belongs to the UQCR11/QCR10 family.Protein type: Mitochondrial; Energy Metabolism - oxidative phosphorylation; Oxidoreductase; Membrane protein, integral; EC 1.10.2.2Chromosomal Location of Human Ortholog: 19p13.3Cellular Component: mitochondrial inner membrane; integral to membraneMolecular Function: electron carrier activity; ubiquinol-cytochrome-c reductase activityBiological Process: cellular metabolic process; generation of precursor metabolites and energy
UniProt Protein Details:
NCBI Summary:
This gene encodes the smallest known component of the ubiquinol-cytochrome c reductase complex, which forms part of the mitochondrial respiratory chain. The encoded protein may function as a binding factor for the iron-sulfur protein in this complex. [provided by RefSeq, Oct 2009]
