The UQCR10 Polyclonal Antibody (CAB4674) is a valuable tool for research involving UQCR10, a subunit of the mitochondrial respiratory chain complex III. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the UQCR10 protein, this antibody allows for detection and analysis in various cell types, making it ideal for studies in mitochondrial function and bioenergetics research.UQCR10 is a crucial component of the electron transport chain in mitochondria, playing a key role in the generation of ATP, the cell's energy currency. Dysregulation of mitochondrial function, including mutations in UQCR10, have been implicated in a variety of diseases, such as cancer, neurodegenerative disorders, and metabolic diseases.
By understanding the function of UQCR10, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets in the field of mitochondrial biology.Overall, the UQCR10 Polyclonal Antibody (CAB4674) offers researchers a reliable tool for studying the role of UQCR10 in mitochondrial function and its implications in various disease contexts. Its high specificity and sensitivity make it a valuable asset for those investigating the complex interplay between mitochondria, energy metabolism, and disease.
Product Name:
UQCR10 Rabbit Polyclonal Antibody
SKU:
CAB4674
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-63 of human UQCR10 (NP_037519.2).
UCRC is a subunit of mitochondrial complex III (ubiquinol-cytochrome c reductase; EC 1.10.2.2), which forms the middle segment of the respiratory chain of the inner mitochondrial membrane (Schagger et al., 1995 [PubMed 8592474]).
Purification Method:
Affinity purification
Gene ID:
29796
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using UQCR10 antibody (CAB4674) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
