The UPP1 Polyclonal Antibody (CAB13051) is a valuable tool for researchers studying Uridine Phosphorylase 1 (UPP1), a key enzyme involved in the metabolism of pyrimidine nucleosides. Raised in rabbits, this antibody is highly specific and reacts strongly with human samples, making it ideal for Western blot applications.UPP1 plays a crucial role in the salvage pathway for nucleotide biosynthesis, making it a promising target for studies in cancer research, metabolic disorders, and nucleoside-based therapies.
By detecting and analyzing UPP1 expression in various cell types, researchers can gain insights into its function and potential implications in disease pathology.Understanding the regulation and activity of UPP1 is essential for developing targeted therapies and diagnostic tools for conditions related to nucleotide metabolism. The UPP1 Polyclonal Antibody offers reliable and accurate results for investigating the role of this enzyme in health and disease.
Product Name:
UPP1 Rabbit Polyclonal Antibody
SKU:
CAB13051
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 89-173 of human UPP1 (NP_001274357.1).
This gene encodes a uridine phosphorylase, an enzyme that catalyzes the reversible phosphorylation of uridine (or 2'- deoxyuridine) to uracil and ribose-1-phosphate (or deoxyribose-1-phosphate). The encoded enzyme functions in the degradation and salvage of pyrimidine ribonucleosides.
Purification Method:
Affinity purification
Gene ID:
7378
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using UPP1 Rabbit pAb (CAB13051) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
