UPB1 Rabbit Polyclonal Antibody (CAB15452)
- SKU:
- CAB15452
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | UPB1 Rabbit Polyclonal Antibody |
SKU: | CAB15452 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human UPB1 (NP_057411.1). |
Sequence: | MAGA EWKS LEEC LEKH LPLP DLQE VKRV LYGK ELRK LDLP REAF EAAS REDF ELQG YAFE AAEE QLRR PRIV HVGL VQNR IPLP ANAP VAEQ VSAL HRRI KAIV EVAA MCGV NIIC FQEA WTMP FAFC TREK LPWT EFAE SAED GPTT RFCQ KLAK NHDM VVVS PILE RDSE HGDV LWNT AVVI SNSG AVLG KTRK NHIP RVGD FNES TYYM EGNL GHPV FQTQ FGRI AVNI CYGR HHPL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | BUP1; UPB1 |
Positive Sample: | Mouse kidney,Mouse liver,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 43kDa |
Observed MW: | 43kDa |
This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.
Purification Method: | Affinity purification |
Gene ID: | 51733 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |