UNG Rabbit Polyclonal Antibody (CAB13155)
- SKU:
- CAB13155
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | UNG Rabbit Polyclonal Antibody |
SKU: | CAB13155 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UNG (NP_550433.1). |
Sequence: | MIGQ KTLY SFFS PSPA RKRH APSP EPAV QGTG VAGV PEES GDAA AIPA KKAP AGQE EPGT PPSS PLSA EQLD RIQR NKAA ALLR LAAR NVPV GFGE SWKK |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15; UNG |
Positive Sample: | Mouse skeletal muscle,Mouse heart,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion, Nucleus. |
Calculated MW: | 35kDa |
Observed MW: | 38kDa |
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Purification Method: | Affinity purification |
Gene ID: | 7374 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |