UNG Rabbit Polyclonal Antibody (CAB1261)
- SKU:
- CAB1261
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | UNG Rabbit Polyclonal Antibody |
SKU: | CAB1261 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human UNG (NP_550433.1). |
Sequence: | MIGQ KTLY SFFS PSPA RKRH APSP EPAV QGTG VAGV PEES GDAA AIPA KKAP AGQE EPGT PPSS PLSA EQLD RIQR NKAA ALLR LAAR NVPV GFGE SWKK HLSG EFGK PYFI KLMG FVAE ERKH YTVY PPPH QVFT WTQM CDIK DVKV VILG QDPY HGPN QAHG LCFS VQRP VPPP PSLE NIYK ELST DIED FVHP GHGD LSGW AKQG VLLL NAVL TVRA HQAN SHKE RGWE QFTD AVVS WLNQ NSNG LVFL LWGS YAQK KGSA IDRK RHHV LQTA HPSP LSVY RGFF GCRH FSKT NELL QKSG KKPI DWKE L |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15; UNG |
Positive Sample: | HeLa,Jurkat,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion, Nucleus. |
Calculated MW: | 35kDa |
Observed MW: | 37kDa |
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Purification Method: | Affinity purification |
Gene ID: | 7374 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |