UNG Monoclonal Antibody [Pk1C12AT] (CPAB0133)
- SKU:
- CPAB0133
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- Pk1C12AT
- Applications:
- WB
- ELISA
Description
UNG Monoclonal Antibody [Pk1C12AT] (CPAB0133)
The UNG Polyclonal Antibody (CPAB0133) is a powerful tool for researchers studying UNG, an essential protein involved in DNA repair and maintenance. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for various applications including Western blotting and immunohistochemistry.UNG, also known as uracil-DNA glycosylase, plays a crucial role in base excision repair by removing uracil from DNA, preventing mutations and maintaining genomic stability. Dysregulation of UNG has been implicated in a variety of diseases including cancer, neurological disorders, and autoimmune conditions.
By targeting UNG with this antibody, researchers can gain insights into its function and potential therapeutic implications in these disease contexts.Overall, the UNG Polyclonal Antibody is a valuable tool for investigating the role of UNG in DNA repair mechanisms and its impact on disease development. Its high reactivity and specificity make it an ideal choice for researchers looking to deepen their understanding of UNG biology and its implications in human health.
Product Name: | UNG Antibody |
Product Sku: | CPAB0133 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human UNG mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human UNG amino acids 1-313 purified from Ecoli. |
Clone: | Pk1C12AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | UNG antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2b |
Background: | E.Coli Uracil DNA Glycosilase (UNG) catalyses the release of free Uracil from Uracil-containing DNA. UNG efficiently hydrolyzes uracil from signle-stranded or double-stranded DNA, but not from oligomers (6 fewer bases). |
Synonyms: | Uracil DNA Glycosilase, Uracil DNA Glycosylase, UNG. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |