The UNC93B1 Polyclonal Antibody (CAB15250) is a valuable tool for researchers studying UNC93B1, a protein involved in immune responses and antigen processing. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting UNC93B1 in human samples and is suitable for use in Western blot applications. By targeting the UNC93B1 protein, this antibody allows for the precise identification and analysis of UNC93B1 expression in various cell types, making it an essential component for investigations in the fields of immunology and infectious diseases.UNC93B1, a key player in the immune system, is responsible for transporting nucleic acid-sensing Toll-like receptors (TLRs) from the endoplasmic reticulum to endolysosomes.
This process is crucial for the recognition of pathogens and initiation of immune responses. Research on UNC93B1 is essential for understanding the mechanisms underlying immune surveillance and host defense against infections. The UNC93B1 Polyclonal Antibody provides researchers with a powerful tool to investigate the functional roles of UNC93B1 in immune signaling pathways, opening up new possibilities for therapeutic interventions targeting immune-related disorders.
Product Name:
UNC93B1 Rabbit Polyclonal Antibody
SKU:
CAB15250
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 450-550 of human UNC93B1 (NP_112192.2).
This gene encodes a protein that is involved in innate and adaptive immune response by regulating toll-like receptor signaling. The encoded protein traffics nucleotide sensing toll-like receptors to the endolysosome from the endoplasmic reticulum. Deficiency of the encoded protein has been associated with herpes simplex encephalitis.
Purification Method:
Affinity purification
Gene ID:
81622
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using UNC93B1 Rabbit pAb (CAB15250) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15S.
