The UNC5D Monoclonal Antibody (PACO61013) is a powerful tool for researchers studying UNC5D, a protein involved in cell guidance and apoptosis. This antibody, produced in-house using cutting-edge technology, has been extensively validated for use in applications such as immunohistochemistry and flow cytometry.UNC5D is a key player in the regulation of cell migration and apoptosis, making it essential for understanding processes like tissue development and tumor progression.
By targeting UNC5D with this monoclonal antibody, researchers can gain valuable insights into its function and potential therapeutic applications in cancer and neurodegenerative diseases.With its high specificity and sensitivity, the UNC5D Monoclonal Antibody (PACO61013) is a valuable tool for any research project exploring the role of UNC5D in cellular processes and disease mechanisms. Get reliable and reproducible results with this top-quality antibody from AssayGenie.
Antibody Name:
UNC5D Antibody (PACO61013)
Antibody SKU:
PACO61013
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Netrin receptor UNC5D protein (90-212AA)
Immunofluorescence staining of Hela cells with PACO61013 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Receptor for the netrin NTN4 that promotes neuronal cell survival (By similarity). Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity). May play a role in apoptosis in response to DNA damage. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity).
