UNC5C Rabbit Polyclonal Antibody (CAB14809)
- SKU:
- CAB14809
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | UNC5C Rabbit Polyclonal Antibody |
SKU: | CAB14809 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-360 of human UNC5C (NP_003719.3). |
Sequence: | EGQS VQKI ACTT LCPV DGRW TPWS KWST CGTE CTHW RRRE CTAP APKN GGKD CDGL VLQS K |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | UNC5H3; UNC5C |
Positive Sample: | SH-SY5Y,293T,Mouse brain,Mouse lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Single-pass type I membrane protein, synapse, synaptosome. |
Calculated MW: | 103kDa |
Observed MW: | 103kDa |
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region.
Purification Method: | Affinity purification |
Gene ID: | 8633 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |