The UNC45B Antibody (PAC050774) is a valuable tool for researchers studying UNC45B, a protein involved in regulating cellular processes such as protein folding and assembly. This polyclonal antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting UNC45B in human samples, making it suitable for a variety of research applications including Western blotting.UNC45B is a crucial component in the chaperone machinery responsible for ensuring proper folding and function of proteins, particularly in the context of muscle development and function.
Dysregulation of UNC45B has been linked to various diseases, including myopathies and cancer, highlighting its importance in cellular homeostasis and disease pathogenesis.By using the UNC45B Antibody, researchers can gain insights into the function and regulation of UNC45B in different cell types and disease states, paving the way for the development of targeted therapies and interventions aimed at restoring protein homeostasis and promoting cellular health.
Antibody Name:
UNC45B Antibody (PACO50774)
Antibody SKU:
PACO50774
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Protein unc-45 homolog B protein (602-710AA)
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO50774 at dilution of 1:100.
Background:
Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development.
Synonyms:
Protein unc-45 homolog B (Unc-45B) (SMUNC45), UNC45B, CMYA4 UNC45
