UMPS Rabbit Polyclonal Antibody (CAB13251)
- SKU:
- CAB13251
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | UMPS Rabbit Polyclonal Antibody |
SKU: | CAB13251 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-260 of human UMPS (NP_000364.1). |
Sequence: | TKDY GTKR LVEG TINP GETC LIIE DVVT SGSS VLET VEVL QKEG LKVT DAIV LLDR EQGG KDKL QAHG IRLH SVCT LSKM LEIL EQQK KVDA ETVG RVKR FIQE NVFV AANH NGSP LSIK EAPK ELSF GARA ELPR IHPV ASKL LRLM QKKE TNLC LSAD V |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | OPRT; UMPS |
Positive Sample: | HT-29,U-87MG,HeLa,LO2,Mouse brain,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, nucleus |
Calculated MW: | 52kDa |
Observed MW: | 57kDa |
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 7372 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |