The ULK2 Polyclonal Antibody (CAB15244) is a crucial tool for researchers studying ULK2, a key regulator of autophagy pathways. This antibody, produced in rabbits, demonstrates high specificity and sensitivity towards human samples, making it ideal for use in Western blotting and immunohistochemistry applications.ULK2 is a critical protein involved in the initiation of autophagy, a process essential for cellular homeostasis and survival. Dysregulation of autophagy has been linked to various diseases, including neurodegenerative disorders and cancer. By targeting ULK2 with this antibody, researchers can gain valuable insights into the molecular mechanisms governing autophagy and its implications in disease pathology.
The ULK2 Polyclonal Antibody enables precise detection and analysis of ULK2 expression in different cell types, allowing for detailed investigation of autophagy processes in various experimental settings. Its reliability and specificity make it a valuable tool for research in cell biology, neuroscience, and cancer biology, providing essential data for understanding autophagy regulation and its potential therapeutic applications.
Product Name:
ULK2 Rabbit Polyclonal Antibody
SKU:
CAB15244
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 390-490 of human ULK2 (NP_001136082.1).
This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified.
Purification Method:
Affinity purification
Gene ID:
9706
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ULK2 Rabbit pAb (CAB15244) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
