The UIMC1 Polyclonal Antibody (CAB7244) is a specialized tool for researchers studying UIMC1, a protein involved in DNA repair and cell cycle regulation. This antibody, developed from rabbit serum, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blot applications.UIMC1, also known as KIAA0101 or p15(PAF), plays a crucial role in maintaining genomic stability and preventing the accumulation of DNA damage. Dysregulation of UIMC1 has been linked to various cancers, making it a promising target for cancer research and therapy development.
By targeting UIMC1 with this antibody, researchers can effectively detect and study its expression levels in different cell types and conditions.By using the UIMC1 Polyclonal Antibody (CAB7244), scientists can gain valuable insights into the role of UIMC1 in DNA repair mechanisms, cell proliferation, and tumor development. This antibody is a valuable tool for advancing our understanding of cancer biology and potentially identifying new therapeutic strategies for cancer treatment.
Product Name:
UIMC1 Rabbit Polyclonal Antibody
SKU:
CAB7244
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human UIMC1 (NP_057374.3).
This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
51720
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using UIMC1 Rabbit pAb (CAB7244) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
